Enhancer and silencer sequences

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Enhancers are nucleotide sequences that can bind various proteins, including activators and potentially repressors, depending on their evolutionary context and interactions with other macromolecules. While traditionally enhancers are associated with activating gene expression and silencers with repression, the binding capabilities of proteins to these sequences are not strictly defined. The function of enhancers is not limited to a single purpose; rather, it is determined by the specific proteins that interact with them. Understanding gene regulation requires looking beyond nomenclature to the dynamic roles of proteins in gene expression.
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In all the stuff I read, enhancer only binds activators while silencer sequences on DNA binds repressors. However, in my biology's slides.. my professor is saying that repressors can bind to both silencers and enhancers.. can anyone confirm this? This is very fishy as I have never read this before and it would kind of defeat the purpose of enhancer sequences no? Thanks!
 
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There is no "purpose of enhancer sequences", these are just nucleotide sequences. They can be bound by whatever protein evolves to recognize them. A protein can enhance or repress gene expression depending on how it interacts with other macromolecules when bound to the nucleotide sequence for which it has affinity. Don't let your thinking about the system be restricted by the nomenclature, the proteins determine what happens.
 

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