Flow Rate of a Deflation Balloon

Click For Summary
SUMMARY

The discussion focuses on deriving the flow rate of a drug delivery infusion pump, specifically a balloon pump filled with 500mL of liquid drug, which has a nominal flow rate of 5mL/hr. Participants suggest using the Poiseuille-Hagen equation to model the flow rate as a function of time, but it is noted that the presence of a resistive element, such as a frit, complicates the application of this equation. Instead, Darcy's law or a modified Poiseuille's law, incorporating a resistive term, is recommended for a more accurate model, considering the elastic nature of the balloon and the decreasing flow rate as it deflates.

PREREQUISITES
  • Understanding of fluid dynamics principles, particularly Darcy's law and Poiseuille's law.
  • Familiarity with the properties of elastomeric materials and their behavior under pressure.
  • Knowledge of viscosity and its impact on fluid flow.
  • Basic mathematical modeling skills to derive flow rate equations.
NEXT STEPS
  • Research the application of Darcy's law in fluid dynamics.
  • Study the Poiseuille-Hagen equation and its limitations in real-world applications.
  • Explore the effects of temperature and viscosity on fluid flow rates in elastic systems.
  • Investigate mathematical modeling techniques for time-dependent flow rates in elastic containers.
USEFUL FOR

This discussion is beneficial for biomedical engineers, fluid dynamics researchers, and anyone involved in the design and optimization of drug delivery systems, particularly those utilizing elastomeric materials.

wuyx724
Messages
5
Reaction score
0
A drug delivery infusion pump is made out of thick synthetic rubber and has a very small outlet. The balloon pump is filled with 500mL liquid drug and is now inflated into a ball shape. The drug will exit from the very small outlet at a nearly (but not always) constant flow rate of 5mL/hr (takes 100hr to deplete).

How can I derive the flow rate as a function of time?
I'd also like to know how the temperature and drug viscosity affect the flow rate.

Someone suggested me to use Poiseuille-Hagen equation, but I need to know more details, especially how I can relate the flow rate to time and establish a model.

Your insight will be highly appreciated!
 
Physics news on Phys.org
Let me know if I'm right: You have a liquid-filled balloon (spherical i guess) which has a little outlet through which liquid is verted outwards. So despite you give a value of a certain flow rate you'd like to know how it evolves with time?

Thanks for clarifying :)
 
Zaphys said:
Let me know if I'm right: You have a liquid-filled balloon (spherical i guess) which has a little outlet through which liquid is verted outwards. So despite you give a value of a certain flow rate you'd like to know how it evolves with time?

Thanks for clarifying :)

That's exactly what I meant!
The "constant flow rate" is only indicative (by product manufacturer). The actual flow rate seems decreasing as balloon deflating (from experimental data).
Looking forward to your solution!
 
Last edited:
Oh! thanks for your trust :) you know its funny because I did something really similar to this yesterday helping another post.

But I'm afraid I need more data because this is a very complex situation and if we want to obtain a practical solution (so that we can even calculate our own time of deplete, for example) we´ll have to do some simplifications in order to modelize the balloon.

May you describe it to me a little more? thanks a lot
 
can you tell me where that post (the similar question you answered yesterday) is located?

sure we can simplify the model to start with, such as a perfect sphrical balloon shape, or even cylinder shape if that makes it easier, water as fluid, constant temperature, etc. I don't know what other information you need.
 
Yes sure, the post is "Need formula/help with mass air flow" at Physics > Classical Physics, it was similar but not the same because there we dealed with a fixed-volume air tank. However some eqs. may help.

The information I need is to modelize the balloon. Whether it decreases in volume as a sphere (or nearly does) or just wrinkle when water is released, or the description of the outlet in size, shape... are data that will allow us to make a good "practical" model of the pump.

Thanks a lot.
 
We can assume either
(1) the balloon remains as a sphere when the volume decreases, or
(2) the balloon keeps one diameter (along the axis of outlet) constant, while the radial dimension decreases.

whichever is easier.

The balloon is connected to a tubing, which has a very small outlet. The whole setup is more like the IV infusion bag, but instead of using a medication bag and the gravitation, we have an elastomeric balloon here.
 

Attachments

  • balloon.JPG
    balloon.JPG
    14.4 KB · Views: 524
Well, I see. The fact is that this is quite complicated because of the elastic nature of the balloon. Picking one of the options, it'd be far easier (1) rather than changing the very geometry of the balloon each second. I´m afraid I can't make a practical model of this if I consider it "realisticly" elastic.

If i come up with an answer for anythig different I tell you.

I'm sorry, :(
 
wuyx724 said:
A drug delivery infusion pump is made out of thick synthetic rubber and has a very small outlet. The balloon pump is filled with 500mL liquid drug and is now inflated into a ball shape. The drug will exit from the very small outlet at a nearly (but not always) constant flow rate of 5mL/hr (takes 100hr to deplete).

How can I derive the flow rate as a function of time?
I'd also like to know how the temperature and drug viscosity affect the flow rate.

Someone suggested me to use Poiseuille-Hagen equation, but I need to know more details, especially how I can relate the flow rate to time and establish a model.

Your insight will be highly appreciated!

It's not just a small hole (at least the devices I have seen)- there is a 'frit' inside that produces a constant resistance. The elastic energy of the balloon produces the driving force, pushing fluid through the porous frit.

The Hagen-Poiseuille equation will not readily apply, due to the presence of the resistive element. A better approach would be Darcy's law (Or Poiseuille's law with a resistive term, sometimes called the Brinkmann equation).
 
  • #10
wuyx724 said:
That's exactly what I meant!
The "constant flow rate" is only indicative (by product manufacturer). The actual flow rate seems decreasing as balloon deflating (from experimental data).
Looking forward to your solution!

That's because the elastic energy of the balloon slowly dissipates as the balloon deflates- think of it as the driving force decreases over time.
 

Similar threads

  • · Replies 1 ·
Replies
1
Views
3K
  • · Replies 5 ·
Replies
5
Views
17K
  • · Replies 4 ·
Replies
4
Views
3K
  • · Replies 1 ·
Replies
1
Views
2K
  • · Replies 4 ·
Replies
4
Views
3K
Replies
2
Views
3K
  • · Replies 6 ·
Replies
6
Views
6K
  • · Replies 1 ·
Replies
1
Views
4K
  • · Replies 1 ·
Replies
1
Views
2K
Replies
2
Views
10K