Flow Rate of a Deflation Balloon

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SUMMARY

The discussion centers on deriving the flow rate of a drug delivery infusion pump, which utilizes a thick synthetic rubber balloon filled with 500mL of liquid drug. The pump maintains a nearly constant flow rate of 5mL/hr for the first 100 hours, after which the flow ceases. Participants suggest using the Poiseuille-Hagen equation to model the flow rate as a function of time and discuss the relationship between temperature, viscosity, and flow rate, noting that increased temperature typically reduces viscosity, thereby enhancing flow rate.

PREREQUISITES
  • Understanding of the Poiseuille-Hagen equation
  • Knowledge of fluid dynamics principles
  • Familiarity with viscosity and its temperature dependence
  • Basic mathematical skills for modeling piecewise functions
NEXT STEPS
  • Research the Poiseuille-Hagen equation and its applications in fluid flow
  • Explore the effects of temperature on viscosity in liquids
  • Study piecewise functions and their graphical representations
  • Investigate the design and functionality of drug delivery infusion pumps
USEFUL FOR

This discussion is beneficial for biomedical engineers, pharmaceutical researchers, and anyone involved in the design and optimization of drug delivery systems.

wuyx724
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A drug delivery infusion pump is made out of thick synthetic rubber and has a very small outlet. The balloon pump is filled with 500mL liquid drug and is now inflated into a ball shape. The drug will exit from the very small outlet at a nearly (but not always) constant flow rate of 5mL/hr (takes 100hr to deplete).

How can I derive the flow rate as a function of time?
I'd also like to know how the temperature and drug viscosity affect the flow rate.

Someone suggested me to use Poiseuille-Hagen equation, but I need to know more details, especially how I can relate the flow rate to time and establish a model.

Your insight will be highly appreciated!
:smile:
 
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wuyx724 said:
A drug delivery infusion pump is made out of thick synthetic rubber and has a very small outlet. The balloon pump is filled with 500mL liquid drug and is now inflated into a ball shape. The drug will exit from the very small outlet at a nearly (but not always) constant flow rate of 5mL/hr (takes 100hr to deplete).

How can I derive the flow rate as a function of time?
I'd also like to know how the temperature and drug viscosity affect the flow rate.
the flow rate is constant meaning it remains at 5ml/hr until 100hr is surpassed. so i'd be a piecewise function that looks like this:

given x is time in hours and y is in ml/hr
if 0<x<100 then y=5
if x>100 then y=0

the temperature and viscosity are almost always related in such a manner
as temperature rises viscosity drops and vice-versa
and if viscosity drops then flow rate is usually increased.
 

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