Freeing all electrons from a wire is theoretically impossible without extreme measures, such as using an atomic bomb, as it would result in a significant release of energy. Attempting to remove electrons will only yield a small number, leading to detectable forces due to the remaining electrons. The Coulomb force equation illustrates the immense energy involved in separating charges, indicating that even a minimal separation can produce substantial force. The discussion raises questions about whether the focus is on all electrons or just the free-moving ones in the metal. Ultimately, the complexities of electron behavior and forces make complete separation unfeasible.