Popular programs for website design include Macromedia Dreamweaver and Microsoft FrontPage, both of which are powerful but come at a cost. Dreamweaver is favored for its HTML capabilities, while FrontPage is often criticized for producing messy code. For minimal coding, AceHTML offers a free version, although it may not match Dreamweaver's quality. Flash is noted for its design flexibility but is discouraged for entire site development due to accessibility issues and potential coding problems. A more effective approach involves hand coding HTML and CSS, using design software like Photoshop for mockups and layouts. While Dreamweaver can facilitate design, it may generate cluttered code if not managed properly. Best practices include using split mode in Dreamweaver to monitor and clean up unnecessary tags. Overall, a combination of tools and hand coding is recommended for optimal website design and functionality.