To resolve the issue of an inaccessible "OK" button in podcast software on a PC, increasing the screen resolution is a key solution. Many applications require a minimum resolution of 1024x768, so if the current setting is lower, such as 800x600 or 640x480, adjusting it can help. Users can access the display settings by right-clicking on the desktop and selecting "Screen Resolution," then changing the resolution to a higher setting. If the button remains unreachable, changing the display orientation temporarily can also provide access. After making the necessary adjustments and saving options, users can revert the resolution and orientation back to their preferred settings. This approach not only resolves the immediate issue but may also enhance overall display quality.