How does particle size affect drag force in colloids?

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Evaluating drag force on a particle in a colloid involves understanding the particle's size relative to the colloid's constituents. For larger particles, traditional fluid dynamics correlations can be applied, while non-Newtonian rheology requires evaluating viscosity based on the particle's shear characteristics. For particles significantly smaller than the colloid constituents, the viscous drag is primarily influenced by the liquid phase, minimizing interactions with the solid components. The viscosity in drag force calculations varies with particle size, necessitating specific adjustments for accurate modeling. Research on particles in blood flow could provide valuable insights into these dynamics.
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How does one evaluate the drag force on a particle moving through a colloid? And how does this depend on the size of the particle compared to the constituents making up the collloid?

For particles much larger than the constituents I can imagine one can just do the same as for a normal fluid and use the various correlations that exist. If the rheology of the colloid is non-Newtonian I can imagine you evaluate the viscosity for a shear, characteristic to the moving particle. But I can also imagine the particle size matters. I would say for particle sizes much smaller than the colloid constituents, the viscous drag experienced by the particle is that of the liquid phase, the interaction with the constituents playing little role. Is that correct?

If so, how does the viscosity in the drag force expressions change with particle size relative to the colloid constituents?

Any experience, refererences, thoughts, comments are welcome!
 
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No colloidal chemists / physicists on this forum with knowledge on the subject?

The specific case I have in mind is that of particles moving through blood, anybody knows of any experiments/simulations reporting on this issue?
 
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