How to Determine Voltage for Nerve Stimulation Using Monophasic Pulse?

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Discussion Overview

The discussion revolves around determining the appropriate voltage for nerve stimulation using a monophasic pulse train. Participants are exploring the relationship between impedance measurements obtained from sinusoidal current and the requirements for monophasic stimulation, including considerations for biomedical applications.

Discussion Character

  • Technical explanation
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • One participant seeks to calculate the required voltage for a current of 5mA using the equation (V=IR) and is inquiring about the appropriate frequency to reference impedance data for a monophasic pulse train at 20 Hz.
  • Another participant questions whether the electrode is intended for human biomedical applications and raises concerns about adhering to safety standards such as UL 544.
  • It is confirmed that the electrode is placed near a nerve, and the participant expresses a need to ensure that the required voltage for stimulation is not excessively high, as this would render the electrode unsuitable.
  • A later reply raises the issue of polarization at the electrode interface potentially affecting impedance and questions the choice of monophasic stimulation, suggesting uncertainty about its standard use in EMG applications.

Areas of Agreement / Disagreement

Participants generally agree on the biomedical context of the electrode and the need to calculate voltage based on impedance. However, there are competing views regarding the implications of polarization on impedance and the appropriateness of monophasic stimulation for the intended application, leaving the discussion unresolved.

Contextual Notes

Participants have not fully explored the implications of polarization on impedance measurements or the specific standards applicable to their biomedical application, indicating potential limitations in their discussion.

tahsid
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I have impedance values for an electrode (used for nerve stimulation) over a wide frequency range using sinusoidal current. Now I have to calculate how much voltage I need to stimulate the electrode at a current of 5mA, using the equation (V=IR). I have to use monophasic pulse train of 5 to 10 pulses, pulse width = 200 micro seconds, inter pulse interval = 5 milli sec and frequency= 20 Hz.
I want to know at what frequency I should take the impedance from the impedance data (obtained using sinusoidal current) corresponding to the frequency of 20 Hz (monophasic pulse train)?
 
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tahsid said:
I have impedance values for an electrode (used for nerve stimulation) over a wide frequency range using sinusoidal current. Now I have to calculate how much voltage I need to stimulate the electrode at a current of 5mA, using the equation (V=IR). I have to use monophasic pulse train of 5 to 10 pulses, pulse width = 200 micro seconds, inter pulse interval = 5 milli sec and frequency= 20 Hz.
I want to know at what frequency I should take the impedance from the impedance data (obtained using sinusoidal current) corresponding to the frequency of 20 Hz (monophasic pulse train)?

Welcome to the PF.

First, is this electrode meant to be used in a human biomedical application? If so, are you designing your circuitry according to the UL 544 safety standard?

Can you please describe the application? What does the electrode get placed on? Depending on the surface, you may not be able to infer monophasic impedance from a balanced AC impedance sweep...
 
Yes, the electrode is meant for biomedical application. the electrode is placed near the nerve.
I have done the impedance measurement of the electrode now I want to calculate how much voltage is required for stimulating this electrode using monophasic current. if the required voltage is too high than this electrode is not suitable.
 
tahsid said:
Yes, the electrode is meant for biomedical application. the electrode is placed near the nerve.
I have done the impedance measurement of the electrode now I want to calculate how much voltage is required for stimulating this electrode using monophasic current. if the required voltage is too high than this electrode is not suitable.

For monophasic current, won't polarization at the interface modify the impedance? Why are you using monophasic stimulation? Is that standard for EMG applications (I don't know)?
 

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