Medical I am a writer working on a novel

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The discussion centers on the topic of necrosis of the epidermis, with a writer seeking information on diseases that can cause this condition. Key diseases mentioned include necrotizing fasciitis, which begins with a wound in the epidermis and can lead to severe tissue damage, and Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), both of which involve significant skin necrosis. The conversation highlights the challenge of finding specific diseases related to epidermal necrosis, as initial searches yielded limited results. Additionally, there is an inquiry about the possibility of developing a vaccination against diseases that cause necrosis if the causative agents are identified. The discussion emphasizes the importance of accurate research for the writer's novel.
Kage Kazumi
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PForums,

I am a writer working on a novel and as part of my job is to research the science behind any idea, I have to make sure is it plausible in real life.

So, my question is in regard to Necrosis of the Epidermis. Is there any known diseases that can cause necrosis on the Epidermis (outer layer of skin)? I did a Google Search for " Necrosis Diseases", and it, mostly just brings up 'Avascular Necrosis' and 'necrosis in regard to plants;' not quite what I'm looking for.

Also if you knew what was causing the Necrosis of a type of disease would it be possible to create a vaccination to counter act the necrosis if the person should come into contact with the disease?

v/Respectfully,
Kage Kazumi
 
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Have you done any research on necrotizing fasciitis? The condition can attack all kinds of underlying tissues, but generally starts with a wound in the epidermis, AFAIK.
 


Well, how about Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)?
 


Googling "epidermal necrosis" brings up a bunch of info, give that a try.
 


turbo said:
Have you done any research on necrotizing fasciitis? The condition can attack all kinds of underlying tissues, but generally starts with a wound in the epidermis, AFAIK.

Well I am looking for actual disease list. I know of a female victim (TV show; see below) who was using a rusted razor and cut herself. The racer had a bacteria on it called "Group A Streptococcus" that caused necrosis. According to reports the lady died due to not getting treatment in time. This information of course came from a TV show; "1,000 Ways to Die," so I make no claim that it is fact ( http://www.spike.com/video-clips/pph8l1/1000-ways-to-die-face-offed" ). She was infected with a bacteria called "Group A Streptococcus."

Ryan_m_b said:
Googling "epidermal necrosis" brings up a bunch of info, give that a try.

Alright.

EDIT

Monique said:
Well, how about Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)?

I'll look into it.

v/Respectfully,
Kage Kazumi
 
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