Did you mean the Jacobian determinant? Then, as AdkinsJr said, it's useful mainly for a change of variables in a multiple integral.
Did you mean the Jacobian matrix? As you know, it's defined as the matrix of partial derivatives of the component functions. For example, if f:\mathbb R^n\rightarrow\mathbb R^m, then you can write f(x)=(f^1(x),\dots,f^m(x), where f^i:\mathbb R^n\rightarrow\mathbb R for i=1,...,m. The Jacobian matrix of f at x is the matrix J_f(x) defined by
J_f(x)^i_j=f^i_{,j}(x)
(The notation means that the element on the ith row, jth column, is the partial derivative of the ith component function with respect to the jth variable). This matrix shows up in the chain rule, which I like to remember in the following forms:
(f\circ g)'(x)=f'(g(x))g'(x)
(f\circ g)'(x)=f_{,i}(g(x))g^i'(x)
(f\circ g)_{,i}(x)=f_{,j}(g(x))g^j_{,i}(x)
(f\circ g)^i_{,j}(x)=(f^i\circ g)_{,j}(x)=f^i_{,k}(g(x))g^k_{,j}(x)
The first equality in the last line is just rewriting the expression in a form that makes it obvious that we can apply the version of the chain rule on the line above. Indices that appear twice in the same expression are summed over (that would be i in the second line, the j in the third, and the k in the fourth). It's conventional to not write any summation sigmas here. (Einstein's summation convention). Note the appearence of the (components of) a Jacobian matrix before the last g in each line. Also note that all of the earlier versions are special cases of the last one.