Is a Cure for AIDS Finally Within Reach?

  • Thread starter Thread starter Tom McCurdy
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The discussion revolves around skepticism regarding a new article on HIV treatment advancements. Participants express concerns about the rapid mutation of the HIV virus, which complicates drug design and necessitates the use of combination therapies, or "cocktails," to effectively target the virus. There is a general sense of pessimism about the potential of new treatments, with references to past reports that have not led to significant breakthroughs. The conversation highlights the ongoing challenges in HIV research, particularly in addressing viral mutation and T-cell loss during infection.
Tom McCurdy
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http://www.sltrib.com/business/ci_3482712

what do you all think/?
 
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I don't know, don't you have a better article that describes the mechanism of action? The problem with the HIV virus is that it mutates rapidly, you can design a drug, but the virus will find a way around it. That's why cocktails are used to treat the disease: target the virus with many agents at once.
 
viral mutation is not the only reason to explain why HIS fails and Tcell loss during HIV infection.

Kaoko
 
Can't say I have much hopes about this, unfortunately.
There have been too many similar reports in the years past, only time will tell of course if this is any better than previous finds.
 
I've been reading a bunch of articles in this month's Scientific American on Alzheimer's and ran across this article in a web feed that I subscribe to. The SA articles that I've read so far have touched on issues with the blood-brain barrier but this appears to be a novel approach to the problem - fix the exit ramp and the brain clears out the plaques. https://www.sciencealert.com/new-alzheimers-treatment-clears-plaques-from-brains-of-mice-within-hours The original paper: Rapid amyloid-β...
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) The structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...

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