If by "isotropic observer" you mean "an observer that sees the spacetime as isotropic", then yes, this is true. At least, it's true of the standard example of a homogeneous and isotropic spacetime, FRW spacetime.
Yes. This is a bit of a strange way of stating it, though; the more standard way of stating it requires you to first set up the standard FRW coordinate chart, and then observe that what you are calling isotropic observers (the more usual term is "comoving" observers) remain at the same spatial coordinates in this chart for all time, hence are "at rest" in this chart.
It's also good to bear in mind that these comoving observers, although they are "at rest" in the standard coordinate chart, are *not* "at rest" relative to each other in other senses in an FRW spacetime. For example, if two comoving observers exchange light signals, they will see the round-trip travel times of the light signals continually increase or decrease (depending on whether they are in an expanding FRW spacetime or a contracting one).