Just submitted my PhD dissertation

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The discussion centers around a graduate student preparing to defend their thesis while transitioning from part-time work in Intelligence to a full-time role post-graduation. The student expresses feelings of being undervalued and exploited during their academic journey. They share details about their thesis, which involves an ion-conductance model of persistence dynamics in biological neurons, highlighting its implications for cognitive functions and muscle contractions. The model focuses on dominant current channels and calcium-dependent channels, intentionally omitting the refractory period for future research. Peers offer congratulations and encouragement, discussing the typical challenges of thesis defenses and the social aspects of post-defense celebrations. The conversation reflects a mix of academic rigor and camaraderie among graduate students.
Pythagorean
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-Defending soon,
-Have a part-time job in Intelligence that I go full-time after officially graduating.
-Starting to see the end of the tunnel.
 
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Go back! It's a trap! They're going to expect you to work from now on!
 
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Noisy Rhysling said:
Go back! It's a trap! They're going to expect you to work from now on!

To be honest, I have felt like cheap and exploited labour through university life as a grad student.
 
Pythagorean said:
To be honest, I have felt like cheap and exploited labour through university life as a grad student.
I knew how to Google, so my lead prof. exploited that.
 
Pythagorean said:
-Defending soon,
-Have a part-time job in Intelligence that I go full-time after officially graduating.
-Starting to see the end of the tunnel.
Congratulations on completing the dissertation and getting it submitted. Best wishes for a successful defense.
 
Good luck Pyth!
 
Congratulations! (Hope the hangover isn't too bad)
 
  • #10
Good luck!
 
  • #11
Greg Bernhardt said:
So what's your thesis?

I made an ion-conductance model of persistence dynamics in a known biological neuron and extended it to the biological network. Persistence dynamics are found across species and typically involve a "switch" (a particular kind of stimulus on the neuron) to switch it from typical threshold-type neuron dynamics to persistent spiking for some duration. It's involved in some cognitive functions (the persistence acts like a sort of information memory) and basically anywhere you have rhythmically contracting muscle (like birth, egg laying, breast-feeding let down, etc).
 
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  • #12
What time frame is the persistence ? seconds ? Hours ?
 
  • #13
jim hardy said:
What time frame is the persistence ? seconds ? Hours ?

The biological neuron goes on for about half hour in a persistent state, then enters a refractory period where it can still respond as a typical threshold-type neuron but can't enter persistence mode for nearly a day. My model doesn't include any of this behavior as I put focus on developing the dominant current channels and their 2nd messengers, as well as the calcium-dependent channels responsible for persistence. So my model goes into persistence indefinitely. The refractory period requires some more elaborate 2nd-messenger modeling, I decided to go to the network and focus on onset and spread in the network and leave refractory period to the next lucky grad student.
 
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  • #14
Congratulations and good luck!
 
  • #15
Congratulations! If you made it this far, you'll almost certainly survive the oral defense unless you have a total meltdown.

Ibix said:
(Hope the hangover isn't too bad)
When I emerged from my dissertation defense, some of my fellow graduate students were waiting to haul me off to a campus watering-hole. :biggrin:
 
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  • #16
Thanks for the congrats, everyone!

I think my defense will go fine. I'll probably get grilled a bit, but that's the nature of the beast.
 
  • #17
Pythagorean said:
My model doesn't include any of this behavior as I put focus on developing the dominant current channels and their 2nd messengers, as well as the calcium-dependent channels responsible for persistence. So my model goes into persistence indefinitely. The refractory period requires some more elaborate 2nd-messenger modeling

Can you send me a pre-print so I can pick it apart and send my objections to the qualifying committee? :oldsmile:

I'll send you a copy of the rebuttal first, before I send it to the committee, promise :oldtongue:
 
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