Momentum is defined as the product of mass and velocity, distinguishing it from inertia, which is a non-quantifiable property of matter reflecting its resistance to changes in motion. In classical mechanics, inertia is often confused with mass, but they are not the same; mass is a measurable quantity. Newton's second law of motion relates force to the change in momentum, indicating that an external force is required to alter momentum. The relationship between force, mass, and acceleration is expressed mathematically, showing that for constant mass, changes in momentum directly correspond to changes in velocity. Understanding these distinctions is crucial for grasping both classical and quantum mechanics concepts.