Protein Sequence Analysis: Identifying Potential Drug Targets from Pathogens

[karthik3k]

Drug target ??

I've got a protein produced by pathogens and I've got its sequence.
How would i know whether it can be a potential Drug target ...

 

[iansmith]

You should do a BLASTP search at http://www.ncbi.nlm.nih.gov/BLAST/
This will give you homologue of you sequence and will give you a possible function including the target. The next step migth be to look for specific pattern at http://ca.expasy.org/tools/scanprosite/

Once you think you migth have a good target you can then do solid phase binding assays and affinity isolation.