At resonance in a series RLC circuit, the instantaneous voltage across the capacitor is equal to the negative instantaneous voltage across the inductor, resulting in a total voltage of zero across both components. This occurs because the impedances of the inductor and capacitor are equal and opposite at the resonant frequency, leading to a phase difference of 180 degrees. The discussion emphasizes the importance of using the resonant frequency to derive the relationship between the voltages. By analyzing the sine wave representations, it is established that the voltages are equal in magnitude but opposite in direction at all times. Thus, the total voltage across the capacitor and inductor sums to zero continuously.