Medical Question about blood transfusion

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The discussion centers on the compatibility of blood donation between genders and the implications for blood transfusions. It highlights that while a rhesus A+ individual can donate to another of the same type, the differences in blood characteristics between men and women, such as hormone levels and cell concentrations, raise questions about the necessity of considering donor gender during transfusions. Participants note that whole blood is rarely used; instead, blood is separated into components like red blood cells and plasma, which minimizes the impact of hormones. Concerns are raised about patients needing frequent transfusions, such as those with thalassemias, who face risks like iron overload. The conversation also touches on veterinary blood transfusions, noting that dogs can receive one transfusion without crossmatching, while cats require careful matching due to existing antibodies.
fluidistic
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Althought I understand that a rhesus A+ can donate blood to a rhesus A+, I don't really understand why a woman can donate blood to a man despite the compatibility of the blood group.
As far as I know there are a lot of differences between women and men's blood. For example hormones, the concentration of red cells and platelets, etc.

What about people who need a blood transfusion by week? Do physicians/nurses care about transfusing blood to a patient from a patient of the same sex? Or they don't even look at that?
 
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Whole blood is rarely transferred blood is spun down and separated out into red blood cells, plasma etc

Hormones don't last that long in your body - any extra eostrogen will soon be destroyed
 
mgb_phys said:
Whole blood is rarely transferred blood is spun down and separated out into red blood cells, plasma etc

Hormones don't last that long in your body - any extra eostrogen will soon be destroyed

I see, thanks.
 
If hormones were a problem - a lot of blood transfusions would be contaminated with epinephrine from somebody sticking a big needle in you!
 
From the OP: "What about people who need a blood transfusion by week?"

Folks who have thalassemias (heritable blood disorders) needing frequent transfusions are indeed at risk (and carefully monitored) for iron overload which can be damaging to organs (heart, liver, etc.).

A little side-topic trivia:
Canine blood allows dogs to receive one "free" transfusion without crossmatching because they don't have naturally occurring antibodies against all the other canine blood types. After the first transfusion, however, dogs can develop those antibodies and must be crossmatched thereafter. Cats do have antibodies against the blood types they are lacking and should be carefully matched and transfused from the start. And then there are the multiple blood types of horses...:-j
 
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