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Salvia Divinorum for treatment of addiction

  1. Oct 11, 2005 #1

    cronxeh

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    Gold Member

    According to this paper http://www.sagewisdom.org/zhangetal.pdf Salvinorin A (active compound in Salvia Divinorum) lowers dopamine levels significantly right after injection.

    And according to "Dopamine hypothesis of schizophrenia" ( http://en.wikipedia.org/wiki/Dopamine_hypothesis_of_psychosis ):

    Could Salvia divinorum be used for treatment of psychosis in amphetamine/cocaine addicts and schizophrenia?
     
  2. jcsd
  3. Oct 12, 2005 #2

    DocToxyn

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    Science Advisor

    Direct use of Salvinorin A may not be the best solution to drug-induced psychoses or schizophrenia. Since the agent itself a hallucinogen, you may simply be trading one symptom for another. Perhaps by studying the specific pharmacological/receptor characteristics of the drug we could more readily create a more useful agent with less deleterious side-effects.
     
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