Simple Question: Units and volume of DNA - Can't get formula correct?

AI Thread Summary
The discussion revolves around calculating the average volume occupied by a single DNA molecule using its molecular weight and density. The formula V = mass/density is highlighted as the correct approach, but confusion arises regarding unit conversions and the relevance of moles. Participants clarify that the molecular weight in grams per mole is essential for determining the mass of one molecule, which can then be used to find the volume. The density of 1.10 g/cm³ is confirmed to be used correctly in the calculations, and it is emphasized that the final answer should reflect the volume of just one DNA molecule, which is significantly smaller than initially calculated. Overall, the method discussed is validated, leading to a clearer understanding of the calculation process.
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Homework Statement



Deoxyribonucleic acid (DNA) is thought to be the chemical compound
responsible for the process of heredity. A sample of DNA was found to have
density 1.10 g/cm3 and its molecular weight was estimated to be
3.04 × 108 g. What is the average volume occupied by one DNA molecule?

Homework Equations


The Attempt at a Solution



I am stuck here. I know V = mass/density

Would I go something like:

3.04 x 10^8 g per mol x (1 mol / 6.022x10^23 molecules) x ( 1 cm^3 / 1.10 g)

No that's not right...dammit

Any help would be great. I know its a simple question, but I need to know exactly how to get the answer.

Thanks all!
 
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Ignore.
 
Last edited:
tms said:
You know exactly how to get the answer: v = m / \rho. What have moles got to do with it?

I thought the correct units for molecular weight is g/mol, and since we are finding the volume of one DNA molecule, I thought I had to do a few conversion factors.
 
tms said:
Ignore.

If I do it that way 3.04 x 10^8 / 1.1 I get... 2.76364 x 10^8 cm^3

which is impossible for just one DNA molecule to occupy that space.
 
nukeman said:

Homework Statement



Deoxyribonucleic acid (DNA) is thought to be the chemical compound
responsible for the process of heredity. A sample of DNA was found to have
density 1.10 g/cm3 and its molecular weight was estimated to be
3.04 × 108 g. What is the average volume occupied by one DNA molecule?


Homework Equations





The Attempt at a Solution



I am stuck here. I know V = mass/density

Would I go something like:

3.04 x 10^8 g per mol x (1 mol / 6.022x10^23 molecules) x ( 1 cm^3 / 1.10 g)

No that's not right...dammit

Any help would be great. I know its a simple question, but I need to know exactly how to get the answer.

Thanks all!

Your method looks okay. Why do think it's not right? Are having difficulty with the unit conversions for grams or cubic centimeters?
 
The molecular weight defines how much mass of something is in a mole, i.e. 6.02(10^23) molecules. You need to normalize the volume to one molecule. Your answer should be correct. Just make sure you put your answer in the units that the answer called for.
 
nukeman said:
I thought the correct units for molecular weight is g/mol, and since we are finding the volume of one DNA molecule, I thought I had to do a few conversion factors.
Forget what I said; I was answering the wrong question.
 
gneill said:
Your method looks okay. Why do think it's not right? Are having difficulty with the unit conversions for grams or cubic centimeters?

Is there a better way to do this. Can you maybe explain?

When you look at this question, what steps are you thinking to do?

Yes, having little issue with last part (1 cm^3 / 1.10g)

So, when I see something like 1.10g/cm^3, if I want to get rid of the g, i would just go...1cm^3 / 1.10 g

Slightly confused :(
 
nukeman said:
If I do it that way 3.04 x 10^8 / 1.1 I get... 2.76364 x 10^8 cm^3

which is impossible for just one DNA molecule to occupy that space.
DNA molecules are huge (although not that huge; I didn't realize you were still looking at my first stupid answer). Compare its molecular weight with that of a more typical molecule.
 
Last edited:
  • #10
tms said:
DNA molecules are huge (although not that huge; I didn't realize you were still looking at my first stupid answer). Compare its molecular weight with that of a more typical molecule.

lol, yea its true. They are pretty big.
 
  • #11
nukeman said:
Is there a better way to do this. Can you maybe explain?
The method that you used is the standard approach, so no need to tinker there.
When you look at this question, what steps are you thinking to do?
Same as you did!
Yes, having little issue with last part (1 cm^3 / 1.10g)

So, when I see something like 1.10g/cm^3, if I want to get rid of the g, i would just go...1cm^3 / 1.10 g

Slightly confused :(
The grams will cancel with another grams earlier in the expression chain. In fact the first item in the chain was the molecular weight given as grams/mol. So the grams in its numerator cancel the grams in the denominator of the density, even though they are separated by other links in the calculation chain.
 
  • #12
Great, thanks. Much better understanding now!
 
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