SIS epidemics transition matrix

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Homework Help Overview

The discussion revolves around a problem related to SIS (susceptible-infected-susceptible) dynamics in a population of 50 individuals. Participants are tasked with determining the transition matrix for the infection probabilities, which include an increase in infected individuals with a probability of 0.1, a decrease with a probability of 0.05, and no change with a probability of 0.85.

Discussion Character

  • Exploratory, Conceptual clarification, Assumption checking

Approaches and Questions Raised

  • Participants explore the structure of the transition matrix and question the clarity of the problem statement. Some suggest that the problem may represent a birth-death process and discuss the implications of corner states in the transition probabilities. There is also discussion about the appropriate state space, whether it should include zero or start from one, and the dimensions of the transition matrix.

Discussion Status

The discussion is ongoing, with various interpretations of the problem being explored. Some participants have provided insights into the nature of the SIS dynamics and the potential structure of the transition matrix, while others are seeking clarification on the definitions and assumptions involved.

Contextual Notes

There are uncertainties regarding the exact wording of the problem and the definitions of terms like SIS dynamics. Participants note the need for clearer definitions and the implications of different assumptions on the state space and transition matrix dimensions.

Mark53
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Homework Statement


[/B]
The population is 50

The diseases is known to follow SIS dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

a) what is the transition matrix P?

The Attempt at a Solution


[/B]
Would this mean my transition matrix would look like this
\begin{bmatrix}0.85 & 0.1 & 0.05 \\ 0.05 & 0.85 & 0.1\\ 0.1 & 0.05 & 0.0.85 \end{bmatrix}

Does this mean my sate space would be (1 to 50)
 
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Mark53 said:

Homework Statement


[/B]
The population is 50

The diseases is known to follow SIS dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

a) what is the transition matrix P?

The Attempt at a Solution


[/B]
Would this mean my transition matrix would look like this
\begin{bmatrix}0.85 & 0.1 & 0.05 \\ 0.05 & 0.85 & 0.1\\ 0.1 & 0.05 & 0.0.85 \end{bmatrix}

Does this mean my sate space would be (1 to 50)

The question makes very little sense as written. Do you mean that each non-infected individual becomes infected with probability 0.1 (independent of others), that each infected individual becomes non-infected with probability .05 (independent of others), and that each individual's status remains unchanged with probability 0.85? If so, you need to have state-space 0,1,2,...,50 (the number of infected individuals at any time). Then, if the state at time ##t## is ##X(t) = k## for some ##k \in \{0,1,\ldots, 50\},## how would you compute the probabilities that ##j## individuals are infected at time ##t+1##? Your transition matrix will be a ##51 \times 51## matrix whose entries are those probabilities.
 
My guess is that the question is this is a birth-death process, where you get one more sick person with probability ##p##, one less sick person with probability ##q##, and stay in same state with probability ##1 - p - q##. The question... could definitely be tightened up in its wording though.

The two exceptions for these transition probabilities are corner states --- i.e. when all 50 people are sick OR when 1 (or 0?) people are sick -- then you need to make appropriate tweaks to ##p## and ##q## respectively. (If it's a zoonotic or infected foreign persons come 'pop in' or what have you, you could still have 0 people sick in your population area yet have reoccurrences of the disease.) So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.
 
StoneTemplePython said:
My guess is that the question is this is a birth-death process, where you get one more sick person with probability ##p##, one less sick person with probability ##q##, and stay in same state with probability ##1 - p - q##. The question... could definitely be tightened up in its wording though.

The two exceptions for these transition probabilities are corner states --- i.e. when all 50 people are sick OR when 1 (or 0?) people are sick -- then you need to make appropriate tweaks to ##p## and ##q## respectively. (If it's a zoonotic or infected foreign persons come 'pop in' or what have you, you could still have 0 people sick in your population area yet have reoccurrences of the disease.) So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.

Yes: that makes a lot of sense, and gives a much more tractable model.
 
StoneTemplePython said:
My guess is that the question is this is a birth-death process, where you get one more sick person with probability ##p##, one less sick person with probability ##q##, and stay in same state with probability ##1 - p - q##. The question... could definitely be tightened up in its wording though.

The two exceptions for these transition probabilities are corner states --- i.e. when all 50 people are sick OR when 1 (or 0?) people are sick -- then you need to make appropriate tweaks to ##p## and ##q## respectively. (If it's a zoonotic or infected foreign persons come 'pop in' or what have you, you could still have 0 people sick in your population area yet have reoccurrences of the disease.) So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.
when multiplying the state space by the transition matrix

How would I know if the individual is infected or not?
 
Mark53 said:
when multiplying the state space by the transition matrix

How would I know if the individual is infected or not?

I'm not sure I follow. The states refer to total number of infected individuals -- knowing whether "the individual" is infected is unrelated / doesn't make sense to ask with respect to the model I'm suggesting. What course is this for? Are you familiar with a birth-death process? You should be able to work out the steady state by hand...

Alternatively, type in the exact problem as I'm just guessing this is a birth death process. The question posed in your original post... leaves a lot to be desired in terms of clarity.
 
StoneTemplePython said:
I'm not sure I follow. The states refer to total number of infected individuals -- knowing whether "the individual" is infected is unrelated / doesn't make sense to ask with respect to the model I'm suggesting. What course is this for? Are you familiar with a birth-death process? You should be able to work out the steady state by hand...

Alternatively, type in the exact problem as I'm just guessing this is a birth death process. The question posed in your original post... leaves a lot to be desired in terms of clarity.

A Health company would like to see how a disease will spread if one infected individual was to arrive in a country with a population of 50 people.

The diseases is known to follow SIS (susceptible-infected-susceptible) dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

Would the state space still be 1 to 50 for this? and a 50x50 transition matrix?
 
Mark53 said:
A Health company would like to see how a disease will spread if one infected individual was to arrive in a country with a population of 50 people.

The diseases is known to follow SIS (susceptible-infected-susceptible) dynamics with the following probabilities

The number of infected individuals increases with probability 0.1

and it decreases with probability 0.05

the probability that nothing happens is 0.85

Would the state space still be 1 to 50 for this? and a 50x50 transition matrix?

I still don't know what course this is for / whether you are familiar with a birth-death process. I have never heard of an SIS dynamic before -- SIS is not a standard term in probability or linear algebra. Providing definitions to the message board for non-standard terms is... generally beneficial.

With respect to your question, which I bolded, what I said before still stands

StoneTemplePython said:
M So the state space is ##\{0, 1, 2, ..., 49, 50\}## or ##\{1, 2, ..., 49, 50\}## depending on whether 0 is allowed.

so its either a 50 x 50 transition matrix or 51 x 51, depending on whether zero is legal.
 
StoneTemplePython said:
I still don't know what course this is for / whether you are familiar with a birth-death process. I have never heard of an SIS dynamic before -- SIS is not a standard term in probability or linear algebra. Providing definitions to the message board for non-standard terms is... generally beneficial.

With respect to your question, which I bolded, what I said before still stands
so its either a 50 x 50 transition matrix or 51 x 51, depending on whether zero is legal.

its a probability course and I have heard of the birth-death process

SIS means going from susceptible to the disease to being infected to returning to being susceptible

given that 1 individual is already infected the state space must be 1 to 50
 
  • #10
It really depends on what you're trying to model and why. Birth-death could makes sense.

You could also model it on an individual person level (susceptible, infected, susceptible), figure out on average the percent of time a person is sick (there will be one eigenvalue = 1, and all others have magnitude less than that in your original 3x3 transition matrix), and from there use linearity of expectations to figure out on average the number of people who are sick, and so on.

The question really could use a re-write for clarity on what exactly it is getting at and perhaps why. (Though that is out of your hands, I know.)
 
  • #11
Mark53 said:
its a probability course and I have heard of the birth-death process

SIS means going from susceptible to the disease to being infected to returning to being susceptible

given that 1 individual is already infected the state space must be 1 to 50

Not necessarily: if eventually the disease can be eradicated, then the state space is {0,1,...,50}. Just because you start at state 1 does not mean that you cannot achieve state 0 in the future.
 

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