It's not the linear speed that causes problems in humans; it's rotational accelerations that produce nausea, vertigo, ataxia, etc.
There is a strong response to rotational velocity, but that has a short time constant.
You could, in principle, spin about all three axes (or really as many as you want), but the acceleration would not be constant or only vertical and the effects would be startling (projectile vomiting). The multi-axis trainer at JSC is tolerable only because the person is at the center of the rotations.