Survival of Red Blood Cells in Varying Salt Concentrations

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Red blood cells can survive in a 0.9% w/v NaCl isotonic solution, which is considered the standard concentration. There is curiosity about whether red blood cells can tolerate varying salt concentrations while still remaining viable for measurement purposes. Understanding the salt content within red blood cells is crucial to determine a safe range of concentrations. The term "isotonic" refers to a solution having the same concentration of solutes as the cells, which is essential for maintaining cell integrity. Clarifying the definition of isotonic is important for accurately addressing the survival of red blood cells in different salt concentrations.
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Is there a range of salt in which red blood cells can survive in an isotonic solution. My current understanding is that they can survive in a 0.9% w/v NaCl isotonic solution. But can that number be varied to a range of different amounts of NaCl in which they can survive for any amount of time long enough to take some measurements?
 
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To answer this, you would have to know something about the salt content of RBCs to determine if there is a normal range of concentrations. Otherwise, I'm wondering if you fully understand the term isotonic. The way your question is worded sounds like you might not...but I could be wrong. Why don't you define isotonic so we can see if you have it right, since that's important for answering this question.
 
A solution with the same concentration of salt as cells.
 
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