HD
divide.
As we go up in atomic number the atoms get larger and larger. The Electrostatic part of the EM force gets larger on an individual proton from the repulsive force of more and more protons. Define this as an increasing weak force. Also dependent on the configuration of those + charges and how they move inside the nucleus. Even the random movement of the electrons outside may have some influence on the net instantaneous weak force working on a individual proton. If all these elements combine such that at some random perfect combination just one proton reaches a weak force push that the strong force cannot hold it back, - well all hell breaks lose.
Once it happens, the end results depend on the EM, Weak, and Strong forces interactions on all the pieces. We see it as radiation, nuclear power, or an explosion.
RB