If the two subsets have no members in common, their intersection will be empty. For example, the union of O = {1, 3, 5, 7, ...} and E = {0, 2, 4, 6, 8, ...} is the set {0, 1, 2, 3, 4, ...}. They have no members in common.
If A = {0, 4, 8, 12, ...}, A U E = E. In this case, set A is a subset of E, so every member of A is automatically a member of E, but not vice versa; there are members of E that aren't also members of A. Because A is a subset of E, their intersection is not empty.