In isolation this doesn't make much sense. The ##\omega << \omega_0## helps, though.
You wrote the eqn of motion for a harmonic oscillator without damping.
So any initial conditions that cause a considerable amplitude can give rise to large acceleration.
If there is some damping, this will be for a certain time only (transient solution), and ultimately only the driving force determines the motion of the oscillator.
Without actually solving the thing and dealing with the initial conditions, it is a little difficult to say very much about it.
Usually the mass is in ##\omega_0## and the equation is written as
$$\ddot x+\omega_0^2 x = F_0\, \cos(\omega t)$$Any solution to the homogeneous equation
$$\ddot x+\omega_0^2 x = 0$$ can be added to a solution of the complete equation. And such a solution has two integration constants, e.g. ##x(0)## and ##\dot x(0)##.
If we follow your account, and let the oscillator move with the driver,
we could try a solution for the inhomogeneous equation
that looks like ##x(t)=A \cos(\omega\, t+\phi)##, fill it in and get
$$A\left (-\omega^2 + \omega_0^2 \right) \cos(\omega\, t+\phi) = F_0 \, \cos(\omega t)$$ Which must be satisfied at all t. From which ##\phi = 0## (more than just in agreement with "pretty much in phase with the driver" -- which gives me the impression some damping is considered to be present...)
and $$ A = {F_0 \over \omega_0^2-\omega^2}$$
[edit]saw your edit but was too far along already...