kptsilva, You have asked a simple question that needs a long and complicated answer. Some folks spend their whole careers studying density contrasts in the universe. Simply put, when you compare a volume of intergalactic space with an equal volume containing a supercluster of galaxies there is a large "density contrast".
With that, I suggest you do some reading and then when you have more specific questions, come right back here and post them. Surely some members here are highly qualified and ready to assist you with any questions or doubts. I offer four references for you:
"The matter power spectrum describes the density contrast of the universe (the difference between the local density and the mean density) as a function of scale. It is the Fourier transform of the matter correlation function. On large scales, gravity competes with cosmic expansion, and structures grow according to linear theory. In this regime, the density contrast field is Gaussian, Fourier modes evolve independently, and the power spectrum is sufficient to completely describe the density field. On small scales, gravitational collapse is non-linear, and can only be computed accurately using N-body simulations. Higher-order statistics are necessary to describe the full field at small scales."
http://en.wikipedia.org/wiki/Matter_power_spectrum
"If we use the virial theorem on galaxies instead of clusters of galaxies then we get a mass-to-luminosity ratio that is about 30. Thus the mass-to-luminosity ratio appears to vary with the size of the region measured, from 3 in the solar neighborhood to 30 in galaxies to 300 in clusters of galaxies. Is there a possibility that for even larger objects the ratio could reach the critical value of 700? For such large regions we cannot use the virial theorem because these regions are still expanding with the Hubble flow. However, we can compute the gravitational acceleration due to the large density contrasts in the nearby superclusters. The density contrast, d(rho)/rho, can be measured by counting galaxies. The gravitational acceleration is proportional to d(rho) which is the measured density contrast times the unknown density. The gravitational acceleration times the age of the Universe gives our peculiar velocity relative to the CMB, which can be determined from the dipole anisotropy of the CMB. Different groups have reached different conclusions about whether the resulting Omega could reach the critical value of 1. But it definitely appears that the dark matter fraction increases with the size of objects at least up to clusters of galaxies (1 Mpc radius)."
http://www.astro.ucla.edu/~wright/density.html
"Primordial matter density contrast and the size of the very early universe in the Quantum Big Bang theory of the cosmological constant"
Authors:Budh Ram
http://arxiv.org/abs/0805.4268
"STRUCTURE FORMATION IN THE UNIVERSE"
http://ned.ipac.caltech.edu/level5/Sept02/Padmanabhan/Pad5.html