- #1
cellec
- 13
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What is Okizaki fragment ?
Does it have anything relating to biology ?
Thanks in advance,
Does it have anything relating to biology ?
Thanks in advance,
Sure, your signature made me wonder. I thought it was a joke because it sounded like kind of a fruit's name than a biological term.loseyourname said:Does this question have anything to do with me?
cellec said:But why are you lagging ?
5' - 3'
5' - - 3'
5' - - - 3'
5' - - - - 3'
etc.
The 3'->5' strand, on the other hand, must be synthesized backward, like this:
3' - 5'
3' - - 5'
3' - - - - 5'
3' - - - - - 5'
3' - - - - - 5' 3' - 5'
3' - - - - - 5' 3' - - 5' {These fragments are referred to as "Okizaki" fragments
3' - - - - - 5' 3' - - - 5'
3' - - - - - - - - - - - 5'
Okizaki fragments are short segments of DNA that are created during DNA replication. They are formed on the lagging strand of the DNA and are later joined together to form a continuous strand of DNA.
Okizaki fragments were discovered by Japanese molecular biologist Reiji Okazaki in the 1960s. He and his team were studying DNA replication in E. coli bacteria and observed the formation of these short fragments during the process.
Okizaki fragments play a crucial role in DNA replication. They are formed due to the discontinuous nature of the lagging strand and allow for efficient and accurate replication of the entire DNA molecule. They are later joined together by the enzyme DNA ligase to form a complete strand of DNA.
The leading strand is replicated continuously in the 5' to 3' direction, while the lagging strand is replicated in short segments, forming Okizaki fragments. This is due to the antiparallel nature of DNA. Additionally, the leading strand only requires one RNA primer, while the lagging strand requires multiple RNA primers for each Okizaki fragment.
Yes, Okizaki fragments are found in all organisms that have DNA as their genetic material. This includes bacteria, plants, animals, and humans. The mechanism of DNA replication and the formation of Okizaki fragments is highly conserved across all living organisms.