The gear train ratio is calculated by dividing the number of teeth on one gear by the number of teeth on another gear. For multiple gears, the overall ratio is found by multiplying the individual ratios together. Each gear in the train affects the overall output, with higher ratios producing more torque but less speed, and vice versa. Worm gears can be used in applications requiring direction changes, but they are less efficient for chaining together compared to spur gears. Understanding these principles helps in making informed decisions about gear selection for specific applications.