What is the purpose of using Concanavalin A coated dishes in cell imaging?

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Concanavalin A (Con A) coated dishes are utilized in cell imaging primarily for their ability to bind glycosyl and mannosyl groups on cell surfaces. This binding facilitates the attachment of cells to the dish, enhancing imaging quality and accuracy. The use of Con A is particularly relevant in studies involving glycoproteins, as it allows for better visualization and analysis of cellular interactions and behaviors.
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Can anyone tell me why are Concanavalin A coated dishes used in cell imaging?

Nancy
 
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nancy189 said:
Can anyone tell me why are Concanavalin A coated dishes used in cell imaging?

Nancy

A laboratory based biologist could give you a more detailed answer, but Concanavalin A is apparently used to bind glycosul and mannosyl groups.

http://jura.wi.mit.edu/sabatini_public/fly_array/ConA.htm
 
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