In Malaysia, all drugs, including cannabis and heroin, are illegal, with possession of 15 grams of certain substances resulting in a mandatory death penalty. In contrast, the U.S. has a complex legal landscape where state laws can conflict with federal laws, particularly regarding marijuana, which is legal in some states for medical use. Discussions highlight the inefficacy of prohibition, suggesting that regulating and taxing substances like marijuana could be more beneficial. The conversation also touches on the moral implications of harsh penalties for drug trafficking, with some arguing that such measures do not effectively deter drug use. Overall, there is a growing belief that marijuana legalization and regulation are inevitable in many regions.