Chemistry When forming a micelle, molecules such as fatty acids

AI Thread Summary
In micelle formation, molecules like fatty acids and detergents arrange themselves with the polar head groups interacting with water and the hydrophobic acyl side chains forming the core. The acyl side chain is identified as a hydrocarbon, typically consisting of more than ten carbon atoms. Low molecular weight surfactants create smaller micelles, while polymer micelles consist of a dense hydrophobic core surrounded by a diluted hydrophilic corona. Understanding the balance between the head group and the acyl chain is crucial for micelle stability. This self-assembly process is significant in various applications, including drug delivery.
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When forming a micelle, molecules such as fatty acids, detergents and lysophospholids form micelles on the basis that the cross sectional area of the head group (I'm guessing the polar part that interacts with water) must be greater than the acyl side chain...but what exactly is the acyl side chain? Is it a hydrocarbon?


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Yes, the acyl side chain is a hydrocarbon (often >10 carbons long) or some other hydrophobic group.
 


Low molecular surfactants form small micelles. The head group is turned to aqueos solution, while hydrophobic tail (alcyl chain, or other) form the core of the micelles.

Polymer micelles are the core-shell structures with diluted corona from hydrophilic chains and dense core of hydrophobic chains.

There is some general information on polymer micelle self-assembly here http://softmat.net/2012/05/26/polymer-micelles-as-drug-carriers/
 
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