The Dihedral Angle Database (DAD) is a comprehensive online repository of dihedral angles found in various molecules, including proteins, nucleic acids, and small molecules. It is used by researchers to study the structure and dynamics of these molecules.
The Dihedral Angle Database is curated by a team of experts who manually extract and validate dihedral angle data from published literature and publicly available databases. They also use computational methods to calculate missing or ambiguous dihedral angles.
Dihedral angles, also known as torsion angles, describe the relative orientation of two planes in a molecule. They are important for understanding the conformational changes and flexibility of molecules, and can provide insight into their biological function and stability.
The Dihedral Angle Database can be used to analyze and compare dihedral angles in different molecules, identify conserved patterns, and study the effects of mutations or ligand binding on dihedral angles. It can also be used to validate molecular models and refine molecular structures.
Yes, the Dihedral Angle Database is freely accessible to all researchers and the general public. No login or subscription is required to search and download data from the database. However, proper citation and acknowledgement of the source is expected when using the data for research purposes.