The discussion centers on determining the number of isomers for the hydrocarbons C6H10 and C6H12. For C6H10, which has either one triple bond or two double bonds, the calculation of isomers is complex, involving graph theory and combinatorics. C6H12, with one double bond, requires a different approach. Participants suggest that drawing out the compounds is the most effective method to identify isomers, rather than relying on theoretical formulas. They emphasize the importance of considering symmetry and stereochemistry to avoid repeats and to account for enantiomers. One participant recommends listing known isomers to identify gaps in the list, while another highlights the significance of categorizing carbons as primary, secondary, tertiary, or quaternary to simplify the process. Overall, the conversation underscores the intricate nature of isomer identification in organic chemistry.