Why do acidic drugs remain unionized in acidic environement?

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Acidic drugs remain unionized in acidic environments and become ionized in basic environments due to the principles of acid/base equilibrium. Conversely, basic drugs ionize in acidic environments and remain unionized in basic conditions. This behavior is foundational in chemistry, specifically in understanding the properties of acids and bases. The discussion highlights the importance of recognizing these chemical principles, which are typically covered in introductory chemistry courses. Additionally, there was a light-hearted exchange regarding the pronunciation of "unionized," indicating a distinction between chemists and non-chemists. The thread was also moved to a more appropriate category, emphasizing its focus on chemistry rather than medical sciences.
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Why do acidic drugs remain unionized in acidic environement, and become ionized in basic environment?

Similarly, why do basic drugs become ionized in acidic environment and remain unionized in basic environment?
 
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This is a pretty basic question about behavior of acids and bases. Short answer: because that's exactly the way they behave. Long answer: please learn about acid/base equilibrium, this is part of GenChem101.

Actually this is a chemistry question, not medical sciences. I am moving the thread.
 
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When I read the subject, I thought you were asking about why acidic drugs were involved in collective bargaining :smile:
 
phinds said:
When I read the subject, I thought you were asking about why acidic drugs were involved in collective bargaining :smile:

That's how you know if someone is a Chemist or not. You ask them to pronounce unionized.

Un-ionized = Chemist
Union-ized = Not a Chemist

:smile:
 
Borek said:
This is a pretty basic question about behavior of acids and bases. Short answer: because that's exactly the way they behave. Long answer: please learn about acid/base equilibrium, this is part of GenChem101.

Actually this is a chemistry question, not medical sciences. I am moving the thread.

Thank you very much for your suggestion and correcting the category. And sorry about my late reply as I have been sick lately.
 

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