BlueBrain Project; Moonbear, anyone?

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Discussion Overview

The discussion centers around the BlueBrain Project, which aims to model the rat brain using computational methods. Participants express interest in the project's goals, methodologies, and potential implications, while seeking additional information and resources.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification

Main Points Raised

  • Some participants mention that the project is a collaboration between IBM and The Ecole Polytechnique Fédérale de Lausanne, focusing on modeling the brain using the BlueGene Supercomputer.
  • There is a suggestion that the rat brain is the initial focus due to the availability of data, with a later goal of modeling other brain areas.
  • One participant expresses curiosity about whether the project will consider developmental stages in rats or focus solely on adult brains.
  • Another participant speculates that starting with adult rats may be more manageable, while also expressing hope that developmental changes and cross-species homology will be included in future models.
  • A participant shares their ambition to contribute to the project and discusses the importance of understanding differential equations and programming for this endeavor.
  • Technical details are mentioned regarding the use of the Hodgkin-Huxley equation to model neocortical columns, with a suggestion that models may evolve to incorporate historical data similar to real neurons.

Areas of Agreement / Disagreement

Participants express various viewpoints regarding the project's focus and methodologies, with no consensus on specific aspects such as developmental considerations or the extent of the model's scope. The discussion remains open-ended with multiple competing ideas.

Contextual Notes

Some limitations include uncertainty about the project's timeline, the specific details of the modeling approach, and the extent of data available for different developmental stages.

neurocomp2003
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Anyone(moonbear) hear about this project...or what its about or links to websites.According to a guest lecturer they are attempting to only model the rat brain...and they'll be modelling it on the BlueGene Supercomputer...

I want to find out more, anyone have anylinks?
 
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Here is the http://bluebrainproject.epfl.ch/index.html"for the project, it's still under construction in some areas.
It's basically a joint venture between IBM and The Ecole Polytechnique Fédérale de Lausanne to model the brain via computer. Here's part of a http://domino.research.ibm.com/comm/pr.nsf/pages/news.20050606_CognitiveIntelligence.html":
Over the next two years scientists from both organizations will work together using the huge computational capacity of IBM’s eServer Blue Gene supercomputer to create a detailed model of the circuitry in the neocortex – the largest and most complex part of the human brain. By expanding the project to model other areas of the brain, scientists hope to eventually build an accurate, computer-based model of the entire brain.
Sounds pretty cool, and right up your alley, neurocomp.
 
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There was an old thread on it around here somewhere. It was back before this forum was formed, so it might still be lurking in the cellar of biology.

I think the rat brain is the only place they can really start for a project like that, because that's the species we have the most data about.
 
thank you for the link DocToxyn...
I"ll have to go search for that thread in the forums too.

I wonder if they'll take child development ages into considerations
or just jump straight itno the adult rats brain.

that'll be my ambitious goal for the next 4 years to try to get on that project some how
hehe
 
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My guess is they'll start with the adult. That's complicated enough. As they build the database, it would be nice to see them add developmental changes as well as information about homology across species, but I don't really know what they have planned.

I'm not sure how much was discussed before on the topic...so if you can't find it, don't spend a lot of time digging for it. I just recall the topic being mentioned before, not how far the discussion got. :redface:
 
neurocomp2003 said:
thank you for the link DocToxyn...
I"ll have to go search for that thread in the forums too.

I wonder if they'll take child development ages into considerations
or just jump straight itno the adult rats brain.

that'll be my ambitious goal for the next 4 years to try to get on that project some how
hehe

Good for you Neurocomp. I contacted someone in charge of the project some time ago (Henry Markram). Initially the focus will be coding the Hodgkin-Huxley equation to model the neocortical columns of the cortex. Later, the models will be allowed to acquire history as do real neurons. Integro-differential equations, in my view, are ideally suited for this task. My suggestion to you if you wish to pursue this is to become very proficient in differential equations and programming. Perhaps one avenue to gain access through the door is to embrace such a mathematical model of the brain and then contact Mr. Markram regarding your interest in such. Good luck.:smile:

Edit: Thank goodness for the edit button! (nobody saw that did you).
 
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