Calculate sublimation rate from pressure rise

AI Thread Summary
The discussion centers around calculating the sublimation rate during freeze drying using pressure rise test data from a chamber. The initial query involves measuring the increase in pressure over 30 seconds after closing an isolation valve and seeking to correlate this pressure change to the rate of vapor accumulation. A participant expresses difficulty in deriving a correct formula, indicating a trial-and-error approach by combining engineering and chemistry equations without confidence in the results. The conversation highlights the need for clarity on how pressure changes relate to sublimation rates in freeze drying processes, emphasizing the importance of accurate calculations in this context.
flysa01
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Hi, I did a pressure rise test on a chamber, where I closed the isolation valve and measured the increase in pressure over 30 seconds.

I want to use this information to calcualte the rate of accumulation of vapour in the chamber. What I'm looking for is the sublimation rate during freeze drying, so how does this increase in pressure correlate to a sublimation rate?

Any suggestions are much appreciated!
 
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Before giving my suggestion I would like to know if you have solved this as I am very late to replay here? If know then I would love to answer you.

powder coat
 
Hiya, I never got it worked out right, do you know how to do it?? In the end I combined a few engineering equations with some chemistry ones and hoped for the best but I knew it wasn't right!
 
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