The area of a triangle can be expressed as 0.5 times the magnitude of the cross-product of two vectors, represented as (1/2)||A x C|| or (1/2)||C x A||. The direction of the vectors does not affect the area calculation since both expressions yield the same magnitude. This relationship holds true regardless of the angle between the vectors, provided angle B is not specifically 90 degrees. The discussion clarifies that the right-hand rule and vector directions are not relevant to the area calculation itself. Overall, the area formula remains consistent across different vector arrangements.