Certain cancers exhibit differing prevalence rates between men and women due to a combination of biological and behavioral factors. Hormonal differences, such as levels of estrogen and testosterone, play a significant role, alongside the presence of sex-specific organs like the prostate in men and breasts in women. For instance, prostate cancer is exclusive to men, being the second most common cancer among them, with risk increasing with age. In contrast, breast cancer is the most prevalent cancer in women. Behavioral factors, particularly historical smoking patterns, have influenced cancer rates; lung cancer incidence in men has peaked while it continues to rise in women due to their later adoption of smoking. Other contributing factors to cancer development include genetics, physical activity, obesity, reproductive history, and hormone exposure, particularly in breast cancer cases. Understanding these dynamics is crucial for early detection and treatment strategies.