Cancer and the Sexes: Why Do Men & Women Differ?

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Certain cancers exhibit differing prevalence rates between men and women due to a combination of biological and behavioral factors. Hormonal differences, such as levels of estrogen and testosterone, play a significant role, alongside the presence of sex-specific organs like the prostate in men and breasts in women. For instance, prostate cancer is exclusive to men, being the second most common cancer among them, with risk increasing with age. In contrast, breast cancer is the most prevalent cancer in women. Behavioral factors, particularly historical smoking patterns, have influenced cancer rates; lung cancer incidence in men has peaked while it continues to rise in women due to their later adoption of smoking. Other contributing factors to cancer development include genetics, physical activity, obesity, reproductive history, and hormone exposure, particularly in breast cancer cases. Understanding these dynamics is crucial for early detection and treatment strategies.
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Why are some cancers more common in men than women and vice versa?
Is this because of hormones or because women have an extra X chromosome?
 
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Well.. more women have lactating breasts than men.. does this count?
 
kalladin said:
Well.. more women have lactating breasts than men.. does this count?
Lactating breasts don't explain why women are immune to prostate cancer though.
 
wasteofo2 said:
Lactating breasts don't explain why women are immune to prostate cancer though.

Well, it indirectly does, since women do not have a prostate gland. It is a purely male organ involved in seminal fluid production. You're not alone in your misconceptions about the prostate, many people think both sexes have one and many more don't know its location and/or function.

As far as prostate malignancies are concerned, this condition is the second most prevalent type of cancer in men and one's risk increases with age. It is not well understood what causes this cancer, but like many, early detection is important and it can be treated.
 
sontag said:
Why are some cancers more common in men than women and vice versa?
Is this because of hormones or because women have an extra X chromosome?
That is because hormone levels are differently in males and females (estrogen, testosteron), organs are different (breast, uterus, ovary, prostate) and also because of behavioural differences (smoking, drinking).

The most common cancer in women is in the breast (33.6%) and in male it is of the prostate (19.4%). In women the second most common is of the colon/rectum (13.2%) and the third most common is the lung/bronchius (7.3%). In men this is reversed: 13.4% and 18.0% respectively. Historically smoking was more popular in men, thus the reversion. For men the incidence of lung cancer has already peaked, for women not yet (since women started the habit of smoking later).

There are also a lot of other factors playing a role in developing tumors, for example in breast tumors: genetics factors, physical activity, young obesity, age at menarchy, age of having children, breast feeding, nr of children, body weight after menopause, progesteron exposure (HRT).
 
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