Chemotherapy is a potent treatment for cancer that utilizes cytotoxic medications to target rapidly dividing tumor cells. This approach, however, also affects normal cells that reproduce quickly, such as hair follicles, leading to hair loss or alopecia. While chemotherapy is primarily associated with cancer treatment, it can also be employed for various other diseases, including autoimmune conditions like lupus nephritis and rheumatoid arthritis, albeit at lower doses to minimize side effects. The term "chemotherapy" encompasses all drug treatments for diseases, including common medications like aspirin. Alopecia from chemotherapy can potentially be mitigated by using cold caps during treatment, which restrict blood flow to hair follicles. Hair typically regrows after the completion of chemotherapy. Despite its effectiveness, chemotherapy is a harsh therapy and is generally reserved for cases where no better alternatives exist.