Dendritic Spines,GABA receptors and plasticity?

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The discussion focuses on the types of GABA receptors found on dendritic spines, their specific locations (head, neck, or shaft), and their role in dendritic spine plasticity. Participants suggest that GABA receptors, particularly GABA(A) and GABA(B), are present on dendritic spines, influencing synaptic transmission and plasticity. The receptors are primarily located on the spine heads, where they can modulate excitatory inputs and contribute to the structural and functional changes associated with synaptic plasticity. A reference to a relevant article from PNAS is provided, highlighting the importance of consulting scientific literature for detailed information. Participants note that while the question is specific, further research through platforms like PubMed could yield comprehensive answers.
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Which type of GABA receptors are present on dendritic spines? Also where are they present on the dendritic spine (i.e. head, neck or shaft)? Also, how do these GABA receptors contribute to dendritic spine plasticity?

Any references would be greatly appreciated.
 
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hivesaeed4 said:
Which type of GABA receptors are present on dendritic spines? Also where are they present on the dendritic spine (i.e. head, neck or shaft)? Also, how do these GABA receptors contribute to dendritic spine plasticity?

Any references would be greatly appreciated.

Here you go, how about this article:

http://www.pnas.org/content/109/5/1708.full.pdf

It was the first article that came up on a pubmed search. For a more general biology or neurology question, your may get personal insight from some of the members. However, your post seems to be very specific. Therefore, my guess is that most members will not have this information right off the top of their heads, and would have to do some research, like on pubmed, to answer your question. This, however, is something that you could probably do yourself just as easily. So, I'm thinking that is your best bet. If, after that, you are still perplexed, then perhaps check back.
 
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