Dendritic Spines,GABA receptors and plasticity?

  • Thread starter Thread starter hivesaeed4
  • Start date Start date
  • Tags Tags
    Plasticity
AI Thread Summary
The discussion focuses on the types of GABA receptors found on dendritic spines, their specific locations (head, neck, or shaft), and their role in dendritic spine plasticity. Participants suggest that GABA receptors, particularly GABA(A) and GABA(B), are present on dendritic spines, influencing synaptic transmission and plasticity. The receptors are primarily located on the spine heads, where they can modulate excitatory inputs and contribute to the structural and functional changes associated with synaptic plasticity. A reference to a relevant article from PNAS is provided, highlighting the importance of consulting scientific literature for detailed information. Participants note that while the question is specific, further research through platforms like PubMed could yield comprehensive answers.
hivesaeed4
Messages
217
Reaction score
0
Which type of GABA receptors are present on dendritic spines? Also where are they present on the dendritic spine (i.e. head, neck or shaft)? Also, how do these GABA receptors contribute to dendritic spine plasticity?

Any references would be greatly appreciated.
 
Biology news on Phys.org
hivesaeed4 said:
Which type of GABA receptors are present on dendritic spines? Also where are they present on the dendritic spine (i.e. head, neck or shaft)? Also, how do these GABA receptors contribute to dendritic spine plasticity?

Any references would be greatly appreciated.

Here you go, how about this article:

http://www.pnas.org/content/109/5/1708.full.pdf

It was the first article that came up on a pubmed search. For a more general biology or neurology question, your may get personal insight from some of the members. However, your post seems to be very specific. Therefore, my guess is that most members will not have this information right off the top of their heads, and would have to do some research, like on pubmed, to answer your question. This, however, is something that you could probably do yourself just as easily. So, I'm thinking that is your best bet. If, after that, you are still perplexed, then perhaps check back.
 
https://www.nhs.uk/mental-health/conditions/body-dysmorphia/ Most people have some mild apprehension about their body, such as one thinks their nose is too big, hair too straight or curvy. At the extreme, cases such as this, are difficult to completely understand. https://www.msn.com/en-ca/health/other/why-would-someone-want-to-amputate-healthy-limbs/ar-AA1MrQK7?ocid=msedgntp&cvid=68ce4014b1fe4953b0b4bd22ef471ab9&ei=78 they feel like they're an amputee in the body of a regular person "For...
Thread 'Did they discover another descendant of homo erectus?'
The study provides critical new insights into the African Humid Period, a time between 14,500 and 5,000 years ago when the Sahara desert was a green savanna, rich in water bodies that facilitated human habitation and the spread of pastoralism. Later aridification turned this region into the world's largest desert. Due to the extreme aridity of the region today, DNA preservation is poor, making this pioneering ancient DNA study all the more significant. Genomic analyses reveal that the...
Whenever these opiods are mentioned they usually mention that e.g. fentanyl is "50 times stronger than heroin" and "100 times stronger than morphine". Now it's nitazene which the public is told is everything from "much stronger than heroin" and "200 times stronger than fentany"! Do these numbers make sense at all? How do they arrive at them? Kill thousands of mice? En passant: nitazene have already been found in both Oxycontin pills and in street "heroin" here, so Naloxone is more...
Back
Top