Even aging can't be so easily cured

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The discussion centers on the complexities of aging, particularly the role of the brain in the aging process. It highlights a theory suggesting that the brain contains circuits that influence aging, implying that transplanting an older brain into a younger body could lead to rapid aging of the new body. However, some participants challenge this notion, arguing that while the brain can affect inflammation, it does not directly control other aging processes like protein glycation or mitochondrial decay. The conversation also touches on cryonics, emphasizing that the procedure should be initiated before death to be effective, rather than as a post-mortem solution. This reflects a broader misunderstanding about the purpose of cryonics, which is to prevent death rather than preserve a deceased body. Additionally, there is a discussion on why aging persists in living organisms and whether it is an unavoidable aspect of evolution. Some mention experiments on mitochondrial DNA that have shown potential ways to manipulate aging in mice, suggesting avenues for future research in anti-aging therapies.
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I just read that

"Even aging can't be so easily cured by replacing someone's
whole body: our brain seems to contain the circuits causing us
to age, and you'd just see the replacement aging very rapidly.
(The circuits aren't just electrical but chemical too. And this
experiment has even, in a sense, been tried, with just the
result I describe here, on animals."

If you connected somebody's (older) brain up to another (younger) brain, (physically) and put the two brains together in a new body, does that mean that the new body would age really quickly?
 
Biology news on Phys.org
Please post a link or some other clue as to where you read that.
 
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Somebody emailed it to me

Somebody was going to start a Cryonics facility in Australia and I started talking to them because I wanted to be frozen after I died

anyways, my sister and I both have an account on this...is there a way to delete one so we don't log in as each other...thanks
 
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Still waiting for a reason to wake the cryopreserved

dreamingofouterspace said:
Somebody emailed it to me
I have been studying human senescence since the year 2000, and I have never heard of a theory explicitly stating that the human brain controls aging rate. One of the things that goes wrong with the body as it ages is excessive inflammation. The central nervous system (brain) can affect inflammation, but it seems to do this in ways that are harmful only when there is something wrong with it (like after a head injury -- car accident victims often suffer from painful and maladaptive inflammatory conditions). If the brain is kept biologically young and healthy, it shouldn't be doing anything to promote harmful inflammation.

Other aging processes include protein glycation and mitochondrial decay. The brain seems to me to have no way of directly influencing these things.



I wanted to be frozen after I died
If you are planning on having your battery of servants wake you up again sometime, you might have to be frozen before you are dead.
groups-beta.google.com/groups?q=wakfer+frozen+before+dead+prevent


--
adman32003 wrote:
> where can i sign up to get my body frozen when I am dead?

Hopefully, nowhere! Because if you are truly dead then nothing can be
done to restore life to your corpse (which is just so much meat).

The whole point of cryonics is intervention in the dying *process*,
before it is complete. Its purpose is thus to *prevent* death. In this
manner it is no different than any other extreme medical procedure.
Cryonics should never be viewed as an alternative form of disposition of
a dead body. Until cryonicists terminate this way of internal thinking,
and external publicity, the movement will not begin to be associated by
the general public with the ideas of greatly extended lifetimes - ideas
which are currently starting to be well accepted by the media.

--Paul Wakfer
--
 
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This is a little off topic but why do living organisms 'age'? How come evolution hasn't bred it out? Is it just something that's totally unavoidable or is it necessary to the survival of a species? I heard (from a slightly unreliable source!) that there's a particular breed of turtle that doesn't age (sorry, I can't remember the name of the breed,) has anyone heard of anything like this or was it a big lie?
 
Hypothetical single-generation species

icvotria said:
How come evolution
Do you mean natural selection?



hasn't bred it out?
If natural selection is understood to work by selecting between generations, the question would seem to imply its own answer.



I heard [...] that there's a particular breed of turtle that doesn't age
There is a breed of tortoise with an exceptionally long lifespan.
http://www.google.com/search?hl=en&q="longest+lived+animal"

--
Longest-Lived Animal: Giant tortoise (Testudo
elephantopus). Its life span is up to 177 years.
--
 
Hmmm, sort of seems like a silly question now in the cold light of day! I've never studied natural selection ( :wink: ) so I only have a very basic understanding of it, but it all seems to work very logically so maybe I should've thought a little harder about that one before posting!
 
There have been experiments on animals mitochondria, which by altering it can make a mouse have symptoms of aging. Such as they can alter the DNA in the mitochondria to make a 3 week old mouse have the body of a 8 year old mouse, really this is all possible because the mitochondria has a different DNA strand than oters cells of the body and it controls the metabolism.

Now if we can harness this we can possibly slow down aging and or speed it up either way you think of it.
 
Successful anti-senescence experiments in mice involving mitochodrial antioxidants

James Nease said:
There have been experiments on animals mitochondria, which by altering it can make a mouse have symptoms of aging.
There have also been experiments involving prevention and reversal of mitochondrial senescence in mice. The experiments were successful, which is why life-extensions today supplement with mitochondrial antioxidants and spin traps.
 

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