Using a Poisson function to fit Gaussian-distributed data can be problematic, as Poisson distributions are designed for specific processes that model rates, where the mean and variance are equal. If the sample mean and variance of the data are close, a Poisson model may be appropriate; otherwise, a Gaussian fit might be better. Transformations like logarithmic or Box-Cox can help make data more symmetric, but should be applied carefully to avoid misinterpretation. The discussion emphasizes the importance of understanding the underlying process before selecting a fitting model. Ultimately, exploring other distributions like Gamma or Chi-square may provide better fits for data that appears Gaussian but has distinct characteristics.