Genes that Cause Human Aging: Telomeres, Klotho & Methuselah

AI Thread Summary
The discussion centers on the genetic factors influencing aging, highlighting that while telomere shortening is commonly believed to be a primary cause, other genes like Klotho and Methuselah also play significant roles. It emphasizes the theory that the accumulation of errors during cell division contributes to aging by damaging DNA, leading to cell death and loss of tissue function. The importance of these genetic factors in the aging process is acknowledged, though the exact degree of their impact remains uncertain. The conversation reflects a broader inquiry into which genes are most critical in the aging process. Overall, the complexity of aging involves multiple genetic influences beyond just telomere shortening.
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What genes cause aging, most people think shortening of telomeres is the main reason of aging, but I know there are more than that, like Klotho, Methuselah. But which fews are more important than others, and what else are there?
 
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Don't forget the long standing theory that accumulation of errors in cell division which causes their failure is responsible for much of the aging.
 
You mean that the DNA of the cells have been damaged so mush that it stops dividing, and when a lot of them are dying at the same time, the tissues are losing its phsiological function, and age? BUt why do you say for much of the aging?
 
That's what I meant, yes, sorry if I expressed it awkwardly. With "much of the aging" I meant to say that it's been considered an important cause, although I wouldn't know just how important.
 
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