Genetics double recombination counted twice in terms of RF

In summary, when mapping out re-combinations of a crossed trihybrid, it is important to consider the proportion of offspring with non-shared parental genotypes. This mating can result in 8 possible genotypes, with 6 being recombinant and 2 being parental. One method for determining the distance between two genes is to calculate the recombination frequency, which takes into account the number of crossover events between the genes. In the case of double recombinants, the frequency should be doubled to accurately determine the distance between the genes.
  • #1
despues357
When mapping out re-combinations of a crossed trihybrid you have to account for the proportion of the offspring who do not share parental genotypes.

Of the 8 possible genotypes stemming from this mating, 6 will be recombinant and two will be of parental genotypes.

Your idea is to Map out the distance between each Subject allele that crossed over by counting their recombinant frequency value as map units (centrimorgans).I'm not sure why you would count double recombinants as twice their frequency simply because there were two cross overs. more like, I can't visualize how that could be interpreted as doubling the perceived distance between these two loci...
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  • #2
To figure out the distance between two genes, you need to figure out the recombination frequency, which is the number of crossover events that happen between the two genes divided by the total number of progeny tested. In the double recombinant, there are two crossover events happening between the V and CV genes. Therefore, you need to take this into account when calculating the recombination frequency.
 

1. What is double recombination in terms of RF in genetics?

Double recombination in terms of RF (recombination frequency) refers to the occurrence of two separate recombination events between two genes on a chromosome. This results in a crossover of genetic material and can be observed and measured through changes in the RF value.

2. How is double recombination counted twice in terms of RF?

In double recombination, two separate crossovers occur between two genes on a chromosome. This means that the RF value will increase by two, as each crossover event adds 50% to the RF value. Therefore, double recombination is counted twice in terms of RF.

3. Why is double recombination important in genetics?

Double recombination is important because it allows for the creation of new genetic combinations and promotes genetic diversity. This process also helps to map the location of genes on a chromosome and can provide valuable information for genetic studies and breeding programs.

4. Can double recombination be used to predict the likelihood of certain traits being inherited?

Yes, double recombination can be used to predict the likelihood of certain traits being inherited. By observing changes in the RF value, researchers can determine the distance between genes on a chromosome and make predictions about the likelihood of certain traits being inherited together or independently.

5. Are there any potential drawbacks to double recombination in terms of RF in genetics?

One potential drawback of double recombination is that it can complicate genetic analyses and make it more difficult to accurately map the location of genes on a chromosome. Additionally, double recombination events may not occur at equal frequencies between all genes, which can lead to discrepancies in RF values and make it challenging to interpret results.

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