Haldane's Dilemma: Resolving Beneficial Mutation Rates

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Haldane's Dilemma raises questions about the rate of beneficial mutations and their ability to explain the evolutionary timeline from early hominids to modern humans. The discussion highlights that the original calculations by Haldane may be flawed due to assumptions about constant population size and the fixation of mutations. Critics argue that these assumptions lead to an overestimation of the cost of natural selection. Specifically, it is noted that Haldane's model incorrectly assumes that two beneficial mutations take twice as long to fixate, neglecting the role of sexual recombination, which allows for simultaneous selection. Recent analyses suggest that when these factors are accounted for, the perceived cost of natural selection may not be as significant as initially thought, indicating that the debate over Haldane's Dilemma remains unresolved but points toward a more nuanced understanding of evolutionary processes.
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http://en.wikipedia.org/wiki/Haldane's_Dilemma
This paper states that rates of beneficial mutations can not account for the time that has passed between the first homonids and humans. Has this been resolved? How?
 
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I think this statement on the wiki page sums it up "The neutrality and factual accuracy of this article are disputed."

The rebutal - "Haldane's "cost of natural selection" stemmed from an invalid simplifying assumption in his calculations. He divided by a fitness constant in a way that invalidated his assumption of constant population size, and his cost of selection is an artifact of the changed population size. He also assumed that two mutations would take twice as long to reach fixation as one, but because of sexual recombination, the two can be selected simultaneously and both reach fixation sooner. With corrected calculations, the cost disappears (Wallace 1991; Williams n.d.). "

http://www.talkorigins.org/indexcc/CB/CB121.html
 
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