Help in understanding effect size in fMRI

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The discussion centers on understanding the implications of a negative effect size in fMRI results, specifically in relation to the article "Differential extrageniculostriate and amygdala responses to presentation of emotional faces in a cortically blind field." The participant seeks clarification on the term "unseen CS-" and its association with low amygdala activation. There is acknowledgment that fMRI measures blood flow to indicate brain activity, but interpretations can vary and may require a deep understanding of specific neural responses. The complexity of fMRI data interpretation is highlighted, emphasizing the need for familiarity with the underlying principles and context of the study.
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Hello everyone, I'm a student of a Master's degree in Neuroscience and I'm preparing a journal club presentation on an article called "Differential extrageniculostriate and amygdala responses to presentation of emotional faces in a cortically blind field". I'm struggling to understand some of the results, in particular what a negative effect size means in fMRI. Is there someone that can explain that to me? I'm referring in particular to this picture of the paper https://d1gqps90bl2jsp.cloudfront.net/content/brain/124/6/1241/F4.large.jpg?width=800&height=600&carousel=1 the one attached).
What can I say about the "unseen CS-"? Why is it so negative? Does it mean that the amygdala has a very low degree of activation?
Thanks to anyone that can help me :)
 

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This appears to be something @DiracPool could help with. I'm confused with your explanation as well. fMRI mesures blood flow in the brain which indirectly shows which brain tissues are active. Interpretation is, IMO, sometimes a bit subjective. Each area seems to require the reader to be in the know how the ground rules are applied. My opinion only. In particular you have to have a solid grip on the particular known aspects of certain kinds of responses.
 

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