Help with understanding about Sordaria

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Sordaria, a haploid ascomycete fungus, can be effectively used in genetic experiments despite its haploid nature. This is possible because Sordaria undergoes a dikaryon phase, allowing for meiosis and genetic recombination, similar to diploid organisms. By manipulating environmental conditions to encourage sexual reproduction, researchers can induce the formation of diploid structures, such as perithecia, by combining different haploid strains. This process enables the application of statistical methods used in diploid species, like Mendel's peas and corn, to analyze genetic problems. Thus, Sordaria serves as a valuable model for studying Mendelian genetics.
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Please help me.
I know that Sordaria is a member of the ascomycete fungi, a group often used in genetics experiments. Yet, Sordaria is haploid.
How can a haploid organism be used to test genetics problems when such things as crossing over require meiosis as the cell goes from a diploid to a haploid stage?
How, then, can we use this haploid organism to test the same genetic problems as with Mendel's peas?
Is it possible to use the same statistical procedures used in diploid species such as corn?
 
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Short answer: Ascomycetes can undergo meiosis. By changing the environment you can encourage either asexual or sexual reproduction.
 
Ester said:
How can a haploid organism be used to test genetics problems when such things as crossing over require meiosis as the cell goes from a diploid to a haploid stage?
You can find insight on your question, in a recent topic about another Ascomycete - Aspergillus (ref recent topic). Both Sordaria and Aspergillus undergo a dikaryon (diploid) phase which leads to genetic recombination.

How, then, can we use this haploid organism to test the same genetic problems as with Mendel's peas?
Is it possible to use the same statistical procedures used in diploid species such as corn?
yes to both, as you will find out by following the above reference, there is a diploid phase in the ascomycete life cycle.
 
How can we use this haploid organism to test the same genetic problems as with Mendel's peas? What types of procedures one would take?
 
Ester said:
How can we use this haploid organism to test the same genetic problems as with Mendel's peas? What types of procedures one would take?
You would need to convince the Sordaria to generate (diploid) perithecia. This is accomplished by bringing to different haploid strains together in the same growing media.This reference may give you some ideas how you might use Sordaria for Mendelian genetic experiments.
 
https://www.discovermagazine.com/the-deadliest-spider-in-the-world-ends-lives-in-hours-but-its-venom-may-inspire-medical-miracles-48107 https://en.wikipedia.org/wiki/Versutoxin#Mechanism_behind_Neurotoxic_Properties https://www.sciencedirect.com/science/article/abs/pii/S0028390817301557 (subscription or purchase requred) he structure of versutoxin (δ-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel...
Popular article referring to the BA.2 variant: Popular article: (many words, little data) https://www.cnn.com/2022/02/17/health/ba-2-covid-severity/index.html Preprint article referring to the BA.2 variant: Preprint article: (At 52 pages, too many words!) https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1.full.pdf [edited 1hr. after posting: Added preprint Abstract] Cheers, Tom

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