How Do NADH and NADPH Differ in Metabolism?

[cthor]

I am studying for an exam tomorrow and am having a hard time understanding a couple of things.

What exactly if the difference in the chemistry and metabloic role of NADH and NADPH?

and

How are metabolic pathways (glycolysis, PPP, gluconeogenesis, citrc acid cycle, and oxid. phosphorylation) connected to each other? and what intermediates connect glycolysis to CAC and glycolysis to gluconeogenesis?

Any help would be greatly appreciated. Thanks

 

[naele]

NADH is used for catabolic pathways while NADPH is used for anabolic pathways. NADPH shows up in the pentose phosphate pathway.

Glycolysis, TCA, and oxidative phosphorylation should be easy to see the connection between each other since they're usually taught as a unit. What is the finaly product of glycolysis? It's that molecule that enters the citric acid cycle. Gluconeogenesis is functionally the opposite of glycolysis and uses most of the same enzymes except for two. A typical exam question is to explain the relationship between the glycolysis enzymes and the gluconeogenesis enzymes that bypass them.

 

[sciencegal]

the way i remember the difference b/t NADH and NADPH is that NADPH is used in photosynthesis...remember the P for photosynthesis...lol just a little study tip